Difference between revisions of "Model organisms"

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== mdx/mTR ==
 
== mdx/mTR ==
 
MDX mice lacking the RNA component of telomerase (mdx/mTR) have shortened telomeres in muscle cells and severe muscular dystrophy that progressively worsens with age.<br />
 
MDX mice lacking the RNA component of telomerase (mdx/mTR) have shortened telomeres in muscle cells and severe muscular dystrophy that progressively worsens with age.<br />
<ref>Read the publication</ref>
+
Read the publication [http://www.ncbi.nlm.nih.gov/pubmed/21145579 here].<br />
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Contact: Alessandra Sacco

Revision as of 18:58, 9 November 2014

This site contains a list of model organisms to study human myopathies. Please feel free to edit/amend the list.

Mdx mutation

MDX mutant mice do not express dystrophin and are used as a model system for Duchenne Muscular Dystrophy.
More information: More information on the mouse model (JAX lab)
Human disease: Duchenne Muscular Dystrophy Contact: Alessandra Sacco

mdx/mTR

MDX mice lacking the RNA component of telomerase (mdx/mTR) have shortened telomeres in muscle cells and severe muscular dystrophy that progressively worsens with age.
Read the publication here.
Contact: Alessandra Sacco